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Illinois vs. Ohio State Prediction, Betting Pick, Latest CFB Odds for Saturday, September 26th
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- Sep 26, 2026, 1:30 PM UTC
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Illinois Ohio State prediction pick betting line September 26 week 4 big ten fighting illini buckeyes columbus horseshoe
Today's Illinois vs. Ohio State prediction, picks, and odds for Week 4 break down the Buckeyes as 27.5-point home favorites with a 53.5 total.
Read Illinois Fighting Illini vs Ohio State Buckeyes predictions, picks and odds in our college football preview for Saturday, Sept. 26.