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Illinois vs. Ohio State odds: 2026 college football picks, Week 4 predictions from proven model
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- Sep 25, 2026, 2:17 PM UTC
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Public university in Columbus, Ohio, US
The Ohio State University is a public research university in Columbus, Ohio, United States. Founded in 1870, it is the flagship institution of the University System of Ohio. It is designated a land-grant, sea-grant, and space-grant university by the government of Ohio.
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Updates, highlights, interviews, pictures, video of Illinois loss at Ohio State in a Big Ten opener on Saturday, Sept. 26, 2026 in Columbus, Ohio.
Get the latest Ohio State vs. Illinois odds, prediction and pick for College Football Week 4, plus kickoff time, TV channel and streaming information.
Today's Illinois vs. Ohio State prediction, picks, and odds for Week 4 break down the Buckeyes as 27.5-point home favorites with a 53.5 total.