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NFL Week 3 Odds and Opening Betting Lines: Rams Giving 2.5 Points in Denver
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- Sep 27, 2026, 10:41 AM UTC
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Get the opening NFL Week-3 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Sept. 24.
Get Week 3 predictions against the spread from CBS Sports experts, plus SportsLine best bets, survivor pool advice, teaser plays and updated odds for every game.
Here are a few betting trends to help you with your wagers in Week 3.